Search on: FAS LIGAND 
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Descriptor English:   Fas Ligand Protein 
Descriptor Spanish:   Proteína Ligando Fas 
Descriptor Portuguese:   Proteína Ligante Fas 
Synonyms English:   CD178 Antigen
CD95 Antigen Ligand
CD95 Ligand
CD95L
Fas Ligand
Fas Ligand (FasL)
FasL Protein
TNF Superfamily, Member 6
Antigen, CD178
Antigens, CD178
CD178 Antigens
Tumor Necrosis Factor Ligand Superfamily Member 6  
Tree Number:   D12.644.276.374.750.249
D12.776.395.550.312
D12.776.467.374.750.249
D12.776.543.550.312
D23.529.374.750.249
Definition English:   A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS. 
History Note English:   2007(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52293 
Unique Identifier:   D053222 

Occurrence in VHL:
 

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